Bogusky, Michael J. : rechercher sur Z-Library

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1

Gene expression informatics —it's all in your mine

Bassett, Douglas E., Eisen, Michael B., Boguski, Mark S.

Journal:

Nature Genetics

Année:

1999

Langue:

english

Fichier:

PDF, 235 KB

english, 1999

2

Genome-wide atlas of gene expression in the adult mouse brain

Lein, Ed S., Hawrylycz, Michael J., Ao, Nancy, Ayres, Mikael, Bensinger, Amy, Bernard, Amy, Boe, Andrew F., Boguski, Mark S., Brockway, Kevin S., Byrnes, Emi J.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 2.89 MB

english, 2006

3

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

Roymarie Ballester, Douglas Marchuk, Mark Boguski, Ann Saulino, Roxanne Letcher, Michael Wigler, Francis Collins

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1.83 MB

english, 1990

4

The solution conformation Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist

Michael J. Bogusky, Adel M. Naylor, Michael E. Mertzman, Steven M. Pitzenberger, Ruth F. Nutt, Stephen F. Brady, Christiane D. Colton, Daniel F. Veber

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 986 KB

english, 1993

5

Discovery of a Potent, CNS-Penetrant Orexin Receptor Antagonist Based on an N,N-Disubstituted-1,4-diazepane Scaffold that Promotes Sleep in Rats

David B. Whitman, Christopher D. Cox, Michael J. Breslin, Karen M. Brashear, John D. Schreier, Michael J. Bogusky, Rodney A. Bednar, Wei Lemaire, Joseph G. Bruno, George D. Hartman, Duane R. Reiss , C

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 418 KB

english, 2009

6

Cover Picture: Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties (ChemMedChem 3/2012)

Dr. Paul J. Coleman, John D. Schreier, Dr. Christopher D. Cox, Michael J. Breslin, David B. Whitman, Dr. Michael J. Bogusky, Dr. Georgia B. McGaughey, Dr. Rodney A. Bednar, Wei Lemaire, Dr. Scott M. D

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 754 KB

english, 2012

7

Localization of phosphorus metabolites and sodium ions in the rat kidney

Ronald T. Bogusky, Michael Garwood, Gerald B. Matson, Galo Acosta, Larry D. Cowgill, Thomas Schleich

Journal:

Magnetic Resonance in Medicine

Année:

1986

Langue:

english

Fichier:

PDF, 733 KB

english, 1986

8

Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization

Stephen F. Brady, John T. Sisko, Kenneth J. Stauffer, Christiana D. Colton, Howard Qiu, Sidney D. Lewis, Assunta S. Ng, Jules A. Shafer, Michael J. Bogusky, Daniel F. Veber, Ruth F. Nutt

Journal:

Bioorganic & Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1995

9

Rational design and synthesis of selective BACE-1 inhibitors

Stephen F. Brady, Satendra Singh, Ming-Chih Crouthamel, M.Katharine Holloway, Craig A. Coburn, Victor M. Garsky, Michael Bogusky, Michael W. Pennington, Joseph P. Vacca, Daria Hazuda, Ming-Tain Lai

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 200 KB

english, 2004

10

Conformational analysis of N,N-disubstituted-1,4-diazepane orexin receptor antagonists and implications for receptor binding

Christopher D. Cox, Georgia B. McGaughey, Michael J. Bogusky, David B. Whitman, Richard G. Ball, Christopher J. Winrow, John J. Renger, Paul J. Coleman

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 534 KB

english, 2009

11

Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonists

Paul J. Coleman, John D. Schreier, Georgia B. McGaughey, Michael J. Bogusky, Christopher D. Cox, George D. Hartman, Richard G. Ball, C. Meacham Harrell, Duane R. Reiss, Thomayant Prueksaritanont, Chri

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 612 KB

english, 2010

12

Synthesis and biological evaluation of unnatural canthine alkaloids

Craig W. Lindsley, Michael J. Bogusky, William H. Leister, Ray T. McClain, Ronald G. Robinson, Stanley F. Barnett, Deborah Defeo-Jones, Charles W. Ross III, George D. Hartman

Journal:

Tetrahedron Letters

Année:

2005

Langue:

english

Fichier:

PDF, 127 KB

english, 2005

13

Structure of synthetic peptide analogues of an eggshell protein of Schistosoma mansoni

C. Russell Middaugh, James A. Ryan, Carl J. Burke, Henryk Mach, Adel M. Naylor, Michael J. Bogusky, Steven M. Pitzenberger, Hanlee Ji, John S. Cordingley, John A. Thomson

Journal:

Protein Science

Année:

1993

Langue:

english

Fichier:

PDF, 4.65 MB

english, 1993

14

NMR studies of novel inhibitors bound to farnesyl-protein transferase

Kenneth S. Koblan, Scott D. Mosser, Charles A. Omer, J. Christopher Culberson, S. Jane Desolms, Elizabeth A. Giuliani, Steven M. Pitzenberger, Michael J. Bogusky

Journal:

Protein Science

Année:

1995

Langue:

english

Fichier:

PDF, 4.31 MB

english, 1995

15

10.1038/1670

Boguski, Mark S., Ermolaeva, Olga, Rastogi, Mohit, Pruitt, Kim D., Schuler, Gregory D., Bittner, Michael L., Chen, Yidong, Simon, Richard, Meltzer, Paul, Trent, Jeffrey M.

Journal:

Nature Genetics

Année:

1998

Langue:

english

Fichier:

PDF, 569 KB

english, 1998

16

Dynamics of the multidomain fibrinolytic protein urokinase from two-dimensional NMR

Oswald, Robert E., Bogusky, Michael J., Bamberger, Michelle, Smith, Richard A. G., Dobson, Christopher M.

Journal:

Année:

1989

Fichier:

PDF, 431 KB

1989

17

Proto-vav and gene expression

Boguski, Mark S., Bairoch, Amos, Attwood, T. K., Michaels, George S.

Journal:

Année:

1992

Fichier:

PDF, 133 KB

1992

18

Characterization of a Solid State Reaction Product from a Lyophilized Formulation of a Cyclic Heptapeptide. A Novel Example of an Excipient-Induced Oxidation

David C. Dubost, Michael J. Kaufman, Jeffrey A. Zimmerman, Michael J. Bogusky, Arthur B. Coddington, Steven M. Pitzenberger

Journal:

Pharmaceutical Research

Année:

1996

Fichier:

PDF, 760 KB

1996

19

Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties

Dr. Paul J. Coleman, John D. Schreier, Dr. Christopher D. Cox, Michael J. Breslin, David B. Whitman, Dr. Michael J. Bogusky, Dr. Georgia B. McGaughey, Dr. Rodney A. Bednar, Wei Lemaire, Dr. Scott M. D

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 445 KB

english, 2012

20

Functional genomics

Michael J Brownstein, Jeffrey M Trent, Mark S Boguski

Journal:

Trends in Biotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 215 KB

english, 1998

21

Synthesis and solution conformation of c(D-Trp-D-Cys(SO3-Na+)-Pro-D-Val-Leu), a potent endothelin-A receptor antagonist

MICHAEL J. BOGUSKY, STEPHEN F. BRADY, JOHN T. SISKO, RUTH F. NUTT, GRAHAM M. SMITH

Journal:

Chemical Biology & Drug Design

Année:

1993

Langue:

english

Fichier:

PDF, 868 KB

english, 1993

22

Discovery of the Dual Orexin Receptor Antagonist [(7 R )-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2 H -1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

Cox, Christopher D., Breslin, Michael J., Whitman, David B., Schreier, John D., McGaughey, Georgia B., Bogusky, Michael J., Roecker, Anthony J., Mercer, Swati P., Bednar, Rodney A., Lemaire, Wei, Brun

Journal:

Journal of Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2010

23

Shaping suvorexant: application of experimental and theoretical methods for driving synthetic designs

McGaughey, Georgia, Bayly, Christopher I., Cox, Christopher D., Schreier, John D., Breslin, Michael J., Bogusky, Michael, Pitzenberger, Steve, Ball, Richard, Coleman, Paul J.

Journal:

Journal of Computer-Aided Molecular Design

Année:

2014

Langue:

english

Fichier:

PDF, 1001 KB

english, 2014

24

Mutant cells with modified trans-acting factor of the uPA gene

Rajput, Bhanu, Hofsletder, Petronella, Bogusky, Ron, Pearson, Davld, Knesel, Jaromir, Altus, Michael, Kiklnis, Zora, Negamine, Yoshkuni

Journal:

Fibrinolysis and Proteolysis

Année:

1989

Langue:

english

Fichier:

PDF, 160 KB

english, 1989

25

Two Tarantula Peptides Inhibit Activation of Multiple Sodium Channels †

Middleton, Richard E., Warren, Vivien A., Kraus, Richard L., Hwang, Jeremy C., Liu, Chou J., Dai, Ge, Brochu, Richard M., Kohler, Martin G., Gao, Ying-Duo, Garsky, Victor M., Bogusky, Michael J., Mehl

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 316 KB

english, 2002

26

3,8-Diazabicyclo[3.2.1]octan-2-one Peptide Mimetics: Synthesis of a Conformationally Restricted Inhibitor of Farnesyltransferase †

Dinsmore, Christopher J., Bergman, Jeffrey M., Bogusky, Michael J., Culberson, J. Christopher, Hamilton, Kelly A., Graham, Samuel L.

Journal:

Organic Letters

Année:

2001

Langue:

english

Fichier:

PDF, 113 KB

english, 2001

27

Cyclopsychotride A, a Biologically Active, 31-Residue Cyclic Peptide Isolated from Psychotria longipes

Witherup, Keith M., Bogusky, Michael J., Anderson, Paul S., Ramjit, Harri, Ransom, Richard W., Wood, Theresa, Sardana, Mohinder

Journal:

Journal of Natural Products

Année:

1994

Langue:

english

Fichier:

PDF, 337 KB

english, 1994

28

Reversible independent unfolding of the domains of urokinase monitored by proton NMR

Bogusky, Michael J., Dobson, Christopher M., Smith, Richard A. G.

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 921 KB

english, 1989

29

Conformational Restriction of Flexible Ligands Guided by the Transferred NOE Experiment: Potent Macrocyclic Inhibitors of Farnesyltransferase

Dinsmore, Christopher J., Bogusky, Michael J., Culberson, J. Christopher, Bergman, Jeffrey M., Homnick, Carl F., Zartman, C. Blair, Mosser, Scott D., Schaber, Michael D., Robinson, Ronald G., Koblan,

Journal:

Journal of the American Chemical Society

Année:

2001

Langue:

english

Fichier:

PDF, 82 KB

english, 2001

30

3-Aminopyrrolidinone Farnesyltransferase Inhibitors: Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency

Bell, Ian M., Gallicchio, Steven N., Abrams, Marc, Beese, Lorena S., Beshore, Douglas C., Bhimnathwala, Hema, Bogusky, Michael J., Buser, Carolyn A., Culberson, J. Christopher, Davide, Joseph, Ellis-H

Journal:

Journal of Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 877 KB

english, 2002

31

Structure-Function Relationships in the Neuropeptide S Receptor

Bernier, Virginie, Stocco, Rino, Bogusky, Michael J., Joyce, Joseph G., Parachoniak, Christine, Grenier, Karl, Arget, Michael, Mathieu, Marie-Claude, O'Neill, Gary P., Slipetz, Deborah, Crackower, Mic

Journal:

Journal of Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 989 KB

english, 2006

32

Linking Yeast Genetics to Mammalian Genomes: Identification and Mapping of the Human Homolog of CDC27 Via the Expressed Sequence Tag (EST) Data Base

Stuart Tugendreich, Mark S. Boguski, Michael S. Seldin and Philip Hieter

Journal:

Proceedings of the National Academy of Sciences

Année:

1993

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1993

33

Fourier Transform Mass Spectrometry and Nuclear Magnetic Resonance Analysis for the Rapid and Accurate Characterization of Hexacosanoylceramide

Ross, Charles, Simonsick, William, Bogusky, Michael, Celikay, Recep, Guare, James, Newton, Randall

Journal:

International Journal of Molecular Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2016